The first time you take the tincture OR truffle, we recommend taking it at night, about an hour before you go to bed. This is so you can gauge if the dosage is right for you.  If it feels too strong, then lower the dose the next time you take it.

Generally, we prefer to microdose in the morning and include the lions mane, niacin and microdose as part of your morning routine.  This can have a great performance enhancement if you like to exercise in the morning.